A Novel In Vivo Method For Quantifying The Interfacial Biochemical Bond Strength Of Bone Implants

Since the breakthrough introduction of osseointegrated implants in the 1980s, great efforts have been made towards surface innovation of clinical implants.



So far, in vivo methods to determine biochemical bonds of the implants are as of yet essentially unexplored and remain challenging. In fact, it is extremely hard to exclusively measure interfacial biochemical bond in vivo.



To the best of our knowledge, the present study may be the first report of an in vivo method to identify an interfacial biochemical bond and quantify its bonding strength, which provide the key of knowledge for the better understanding on biochemical bonding in implant integration.




Proceedings of the Royal Society B: Biological Sciences


Proceedings B is the Royal Society's flagship biological research journal, dedicated to the rapid publication and broad dissemination of high-quality research papers, reviews and comment and reply papers. The scope of the journal is diverse and is especially strong in organismal biology.


rspb.royalsocietypublishing